US Open champion Emma Raducanu will meet Daria Saville from Australia in her opening encounter at the Abierto Zapopan in Guadalajara.
The world No 12 is the top seed at the WTA 250 event and world No 426 Saville will be her first opponent since her defeat to Danka Kovinic at Melbourne Park.
If she comes through the first round she will meet Zhu Lin from China or a qualifier in the second round with former US Open champion Sloane Stephens a possible opponent in the quarter-finals.
Camila Osorio and Zheng Qinwin are the other seeds in the top half of the draw and if the draw goes to plan, they would need in the last eight with either Raducanu or Stephens in the semi-final.
Second seed Madison Keys faces Harmony Tan from France in her opener.