Arthur Ashe Stadium
(1) Daniil Medvedev (Rus) v Stefan Kozlov (USA), Leolia Jeanjean (Fra) v (12) Cori Gauff (USA), Danka Kovinic (Mne) v Serena Williams (USA), (23) Nick Kyrgios (Aus) v Thanasi Kokkinakis (Aus)
Louis Armstrong Stadium
(24) Francisco Cerundolo (Arg) v Andy Murray (Gbr), (7) Simona Halep (Rom) v Daria Snigur (Ukr), (20) Madison Keys (USA) v Dayana Yastremska (Ukr), (4) Stefanos Tsitsipas (Gre) v Daniel Elahi Galan (Col), (14) Leylah Annie Fernandez (Can) v Oceane Dodin (Fra)
Grandstand
Tatjana Maria (Ger) v (3) Maria Sakkari (Gre), Harmony Tan (Fra) v Bianca Vanessa Andreescu (Can), Alexander Ritschard (Swi) v (6) Felix Auger-Aliassime (Can), (10) Taylor Harry Fritz (USA) v Brandon Holt (USA)
Court 4
Sebastian Korda (USA) v Facundo Bagnis (Arg), (15) Beatriz Haddad Maia (Bra) v Ana Konjuh (Cro), Alex Molcan (Svk) v Thiago Moura Monteiro (Bra), Nadia Podoroska (Arg) v Anna Karolina Schmiedlova (Svk)
Court 5
Jeffrey John Wolf (USA) v (16) Roberto Bautista Agut (Spa), Stan Wawrinka (Swi) v Corentin Moutet (Fra), (5) Ons Jabeur (Tun) v Madison Brengle (USA), Arantxa Rus (Ned) v (31) Shelby Rogers (USA)
Court 6
Zhizhen Zhang (Chn) v Tim Van Rijthoven (Ned), Camila Giorgi (Ita) v Anna Bondar (Hun), Elena Gabriela Ruse (Rom) v Daria Saville (Aus), Benjamin Bonzi (Fra) v Ugo Humbert (Fra)
Court 7
John Millman (Aus) v Eduardo Nava (USA), Filip Krajinovic (Ser) v (18) Alex De Minaur (Aus), Karolina Muchova (Cze) v Ajla Tomljanovic (Aus), Sara Bejlek (Cze) v Ludmilla Samsonova (Rus)
Court 8
(18) Veronika Kudermetova (Rus) v Donna Vekic (Cro), Tomas Martin Etcheverry (Arg) v Pablo Andujar (Spa), Tomas Machac (Cze) v (21) Botic Van de Zandschulp (Ned)
Court 9
Alejandro Tabilo (Chi) v Kamil Majchrzak (Pol), Elizabeth Mandlik (USA) v Tamara Zidansek (Slo), Magdalena Frech (Pol) v Rebecca Marino (Can), Jack Draper (Gbr) v Emil Ruusuvuori (Fin)
Court 10
Yoshihito Nishioka (Jpn) v Alejandro Davidovich Fokina (Spa), Ben Shelton (USA) v Nuno Borges (Por), Fernanda Contreras Gomez (Mex) v (23) Barbora Krejcikova (Cze), Viktoria Kuzmova (Svk) v Sara Sorribes Tormo (Spa)
Court 11
(29) Tommy Paul (USA) v Bernabe Zapata Miralles (Spa), Coco Vandeweghe (USA) v Maryna Zanevska (Bel), (27) Martina Trevisan (Ita) v Evgeniya Rodina (Rus), Lorenzo Sonego (Ita) v Jordan Thompson (Aus)
Court 12
(29) Alison Riske-Amritraj (USA) v Eleana Yu (USA), Kyle Edmund (Gbr) v (5) Casper Ruud (Nor), Harriet Dart (Gbr) v (10) Daria Kasatkina (Rus), Alexander Bublik (Kaz) v Hugo Gaston (Fra)
Court 13
Ann Li (USA) v Maria Camila Osorio Serrano (Col), Yibing Wu (Chn) v (31) Nikoloz Basilashvili (Geo), (27) Karen Khachanov (Rus) v Denis Kudla (USA), Shuai Zhang (Chn) v (30) Jil Belen Teichmann (Swi)
Court 14
16:00: Rebecca Peterson (Swe) v Anna Kalinskaya (Rus), Marton Fucsovics (Hun) v (30) Maxime Cressy (USA), Christian Garin (Chi) v Jiri Lehecka (Cze), Elina Avanesyan (Rus) v Aleksandra Krunic (Ser)
Court 15
Quentin Halys (Fra) v Arthur Rinderknech (Fra), Nuria Parrizas-Diaz (Spa) v Dalma Galfi (Hun), Diane Parry (Fra) v Xiyu Wang (Chn), Aljaz Bedene (Slo) v Pedro Cachin (Arg)
Court 17
Kamilla Rakhimova (Rus) v (17) Caroline Garcia (Fra), Nicolas Jarry (Chi) v (13) Matteo Berrettini (Ita), (12) Pablo Carreno-Busta (Spa) v Dominic Thiem (Aut), Jaqueline Adina Cristian (Rom) v (2) Anett Kontaveit (Est)